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Tnf

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  • HY-P7303
    TNF-alpha/TNFSF2 Protein, Rhesus macaque
    1 Publications Verification

    rRhTnf-α; Cachectin; Tnf-α; TnfA

    		 Rhesus Macaque E. coli
    Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. TNF-alpha/TNFSF2 Protein, Rhesus macaque is a recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E. coli.
  • HY-P72444
    TNF RII/TNFRSF1B Protein, Rhesus Macaque (HEK293, His)

    Tnf-R2; CD120b; Tumor necrosis factor receptor superfamily member 1b; p75; Tnfr2

    		 Rhesus Macaque HEK293
    TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNF RII/TNFRSF1B Protein, Rhesus Macaque (HEK293, His) is expressed by HEK293 and has a transmembrane region (L23-D257) with 6*His tag at the C-terminus.
  • HY-P77498
    TNF RII/TNFRSF1B Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc)

    Tnf-R2; CD120b; Tumor necrosis factor receptor superfamily member 1b; p75; Tnfr2

    		 Rhesus Macaque HEK293
    TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNF RII/TNFRSF1B Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is expressed by HEK293 and has a transmembrane region (M1-D257) with hFc tag at the C-terminus.
  • HY-P72442
    BAFF/TNFSF13B Protein, Rhesus Macaque (HEK293, Fc)

    Tnf superfamily member 13b; TnfSF13B; TNLG7A

    		 Rhesus Macaque HEK293
    The BAFF/TNFSF13B protein is a member of the tetraspanin (TM4SF) family and is actively involved in a variety of cellular processes. BAFF/TNFSF13B is a component of the tetraspanin superfamily and is critical for cell adhesion, migration, and signaling events. BAFF/TNFSF13B Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-hFc labeled tag. The total length of BAFF/TNFSF13B Protein, Rhesus Macaque (HEK293, Fc) is 152 a.a., with molecular weight of 45-55 kDa.
  • HY-P701047
    TL1A/TNFSF15 Trimer Protein, Cynomolgus/Rhesus macaque (HEK293, His)

    TL1A; VEGI-251; TnfSF15; TL1; VEGI; VEGI192A; Tnf superfamily member 15

    		 Rhesus Macaque;Cynomolgus HEK293
    The TL1A/TNFSF15 Trimer Protein, a vital member of the tumor necrosis factor family, is crucial for immune regulation and cellular responses. Its study enhances our understanding of immune modulation, offering potential applications in immunological assays and therapeutic developments. TL1A/TNFSF15 Trimer's classification within the tumor necrosis factor family underscores its unique contributions to T cell activation and co-stimulation. Further exploration holds promise for enhancing our knowledge of its role in both normal immune function and pathological conditions. TL1A/TNFSF15 Trimer Protein, Cynomolgus/Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque, cynomolgus-derived TL1A/TNFSF15 Trimer protein, expressed by HEK293, with N-His labeled tag. The total length of TL1A/TNFSF15 Trimer Protein, Cynomolgus/Rhesus macaque (HEK293, His) is 180 a.a., with molecular weight of 25-35 kDa.
  • HY-P77256
    TRAIL/TNFSF10 Protein, Rhesus Macaque

    Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand; Apo-2L; Tnf-Related Apoptosis-Inducing Ligand; Protein TRAIL; CD253; TnfSF10; APO2L; TRAIL

    		 Rhesus Macaque E. coli
    TRAIL Protein (TNFSF10), a member of the TNF superfamily, is a type II transmembrane protein. TRAIL Protein mainly interacts with TRAIL-R1 and TRAIL-R2, and induces apoptosis in tumor or infected cells. TRAIL Protein also binds with DR4, DR5, and OPG. TRAIL Protein can recruit FADD and further recruit and activates caspase-8 after binding to DR4 or DR5. Besides, TRAIL may also trigger nonapoptotic signaling through activating pro-inflammatory pathways. TRAIL protein is mainly expressed on surface of immune cells, such as cytotoxic T cells and natural killer (NK) cell. TRAIL/TNFSF10 Protein, Rhesus Macaque is a recombinant Rhesus Macaque TRAIL (V114-G281) without any tag, which is expressed in E. coli.

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